Ablation of calcitonin/calcitonin gene-related peptide- impairs fetal magnesium but not calcium homeostasis
نویسندگان
چکیده
Kirsten R. McDonald, Neva J. Fudge, Janine P. Woodrow, James K. Friel, Ana O. Hoff, Robert F. Gagel, and Christopher S. Kovacs Faculty of Medicine Endocrinology, Memorial University of Newfoundland, St. John’s, Newfoundland A1B 3V6; Department of Biochemistry and Pediatrics, Memorial University of Newfoundland, St. John’s, Newfoundland A1B 3X9, Canada; and University of Texas MD Anderson Cancer Research Center, Houston, Texas 77030
منابع مشابه
Ablation of calcitonin/calcitonin gene-related peptide-alpha impairs fetal magnesium but not calcium homeostasis.
We used the calcitonin/calcitonin gene-related peptide (CGRP)-alpha gene knockout model (Ct/Cgrp null) to determine whether calcitonin and CGRPalpha are required for normal fetal mineral homeostasis and placental calcium transfer. Heterozygous (Ct/Cgrp(+/-)) and Ct/Cgrp null females were mated to Ct/Cgrp(+/-) males. One or two days before term, blood was collected from mothers and fetuses and a...
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تاریخ انتشار 2004